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扁塑藤素

分析標準品,HPLC≥98%

pristimerin

CAS號：1258-84-0

分子式：C30H40O4

分子量：464.64

MDL：MFCD01711331

別名：扁蒴藤素;Celastrol-methylether; pristimerine

產品介紹

熔點：218-219 ℃

沸點：607.7℃ at 760mmHg

外觀：紅色針狀晶體

溶解性：可溶于甲醇、乙醇、DMSO等有機溶劑

儲存條件：2-8℃

注意：部分產品我司僅能提供部分信息，我司不保證所提供信息的權威性，僅供客戶參考交流研究之用。

參考文獻(8篇)

8. [IF=4.1] Kai-lang Mu et al."Analysis of Chemical Constituents of Miao Ethnomedicine Heiguteng Zhuifeng Huoluo Capsule (HZFC) and the Discovery of Active Substances in the Treatment of Rheumatoid Arthritis."ACS Omega".2024;9(9):10860–10874

7. [IF=9.3] Li Tao et al."Natural pentacyclic triterpenoid from Pristimerin sensitizes p53-deficient tumor to PARP inhibitor by ubiquitination of Chk1."PHARMACOLOGICAL RESEARCH".2024 Mar;201:107091

6. [IF=7.9] QinWei Huang et al."DCTPP1, a Reliable Q-Biomarker for Comprehensive Evaluation of the Quality of Tripterygium Glycoside Tablets Based on Chemical References."PHYTOMEDICINE.2023 Jul;:154972

5. [IF=6.069] Honglin Jia et al."Tumor-Derived PD-L1+ Exosomes with Natural Inflammation Tropism for Psoriasis-Targeted Treatment."BIOCONJUGATE CHEMISTRY.2023;XXXX(XXX):XXX-XXX

4. [IF=2.039] Yingxiang Liu et al."Pristimerin Induces Autophagy‐Mediated Cell Death in K562 Cells through the ROS/JNK Signaling Pathway."Chem Biodivers. 2019 Aug;16(8):e1900325

3. [IF=4.114] Zhao  Qun et al."Pristimerin induces apoptosis and autophagy via activation of ROS/ASK1/JNK pathway in human breast cancer in vitro and in vivo."Cell Death Discov. 2019 Aug;5(1):1-13

2. [IF=4.679] Zhuangzhuang Jiang et al."Pristimerin synergizes with gemcitabine through abrogating Chk1/53BP1-mediated DNA repair in pancreatic cancer cells."Food Chem Toxicol. 2021 Jan;147:111919

1. [IF=5.34] Qun Zhao et al."Pristimerin induces apoptosis and tumor inhibition of oral squamous cell carcinoma through activating ROS-dependent ER stress/Noxa pathway."Phytomedicine. 2021 Nov;92:153723

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